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Renew or Sign in Subscribe or Renew Search site Keyword New England Journal of Medicine Search Home Specialties Specialties Selected specialties View all specialties Allergy/ Immunology Cardiology Dermatology Emergency Medicine Endocrinology Gastroenterology Genetics Geriatrics/ Aging Hematology/ Oncology Infectious Disease Nephrology Neurology/ Neurosurgery Obstetrics/ Gynecology Pediatrics Primary Care/ Hospitalist Psychiatry Pulmonary/ Critical Care Rheumatology Surgery View all specialtiesCardiologyHematology/OncologyInfectious Disease Topics Topics Selected Topics View all topics Health Policy Medicine and Society Case Studies in Social Medicine Data Sharing Pain Management Frontiers in Medicine Coronavirus Climate Crisis and Health Zika Virus Ebola Virus E-Cigarettes and Vaping-Related Disease View all topicsHealth PolicyMedicine and SocietyPain ManagementEbola Virus Multimedia Multimedia Selected Multimedia View all multimedia Audio Clinical Practice Audio Interviews Audio Summaries Image Challenge Images in Clinical Medicine Interactive Medical Cases Quick Takes Videos in Clinical Medicine Visual Abstracts View all multimedia Lung-Cancer Mortality with Volume CT Screening Examining the Ethics of Organ Donation A Rapid Change in Pressure Focused Cardiac Ultrasonography Current Issue Current Issue Current Issue Current Issue February 6, 2020 Vol. 382 No. 6 Recent Issues January 30, 2020 Vol. 382 No. 5 January 23, 2020 Vol. 382 No. 4 January 16, 2020 Vol. 382 No. 3 Browse full issue index Browse recently published Browse full issue index Recently Published Articles Organ Donation after Medical Assistance in Dying — Canada’s First Cases First Case of 2019 Novel Coronavirus in the United States M.L. Holshue et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany C. Rothe et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia Q. Li et al. Retraction: Banegas JR et al. Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality. N Engl J Med 2018;378:1509-20. J.R. Banegas et al. Influenza in U.S. Detention Centers — The Desperate Need for Immunization C. Foppiano Palacios et al. Browse recently published Learning/CME Learning/CME View all learning/CME CME Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer Lower versus Traditional Treatment Threshold for Neonatal Hypoglycemia Challenge Yourself Interactive Medical Cases Image Challenge Videos in Clinical Medicine View all learning/CME Other NEJM Group Learning Hand Hygiene Essential information students and residents need to approach residency with confidence: practical training information, career guidance, insightful discussions. Effective, adaptive learning that helps you prepare for certification, maintain competency, and sharpen clinical decision-making while earning CME and MOC. Author Center Subscribe or Renew Keyword Advanced Search Original Article Brief Report First U.S. Confirmed Case of 2019-nCoV Infection M.L. Holshue and Others A healthy 35-year-old man who had visited Wuhan, China, presented with cough and fever that progressed to pneumonia. This report describes the diagnosis, clinical course, and management of the condition. The case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels. Jan 31 Original Article Early Transmission Dynamics of 2019-nCoV Q. Li and Others The authors provide an epidemiologic analysis of the first 425 confirmed cases of infection with the novel coronavirus in Wuhan, China. This analysis provides estimates of the epidemic doubling time and the basic reproductive number and shows clear evidence of sustained human-to-human transmission. Jan 29 Correspondence Human-to-Human Coronavirus Transmission in Vietnam L.T. Phan and Others The authors describe transmission of 2019-nCoV from a father, who had flown with his wife from Wuhan to Hanoi, to the son, who met his father and mother in central Vietnam and shared a hotel room with them for 3 days. The findings suggest that the incubation period in the son may have been 3 days or less. Jan 28 Original Article Brief Report A Novel Coronavirus in China N. Zhu and Others The authors report the emergence and isolation of a previously unknown betacoronavirus, the seventh member of the family of coronaviruses that infect humans, in Wuhan, China. Findings in three patients are described. Jan 24 Editorial Another Decade, Another Coronavirus Editorial Medical Journals and the Coronavirus Outbreak E.J. Rubin and Others The editors announce expedited handling for submitted manuscripts describing the 2019-nCoV outbreak and make broad recommendations for speed, transparency, and data sharing. Jan 27 Review Article Effects of Intermittent Fasting on Health and Aging R. de Cabo and M.P. Mattson Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-based energy, with increased stress resistance, increased longevity, and a decreased incidence of diseases, including cancer and obesity. Dec 26 Correspondence Organ Donation after Euthanasia I.M. Ball and Others Medical assistance in dying followed by organ donation is new to North America. If chosen, this path offers potential donors the opportunity to fulfill their last requests and may also affect transplant waiting lists. This letter from Canada discusses organ donation after euthanasia and its implications. Feb 06 Recent Information on the 2019 Novel Coronavirus (2019-nCoV) Image of the Week Extranodal Natural Killer T-Cell Lymphoma — This 53-year-old man presented with relapsing fevers, dyspnea, and rapidly progressive skin lesions. Original Research Original Article Lung-Cancer Screening in the NELSON Trial H.J. de Koning and Others High-risk persons were screened for lung cancer in a population-based, randomized, controlled trial that involved volume-based nodule management for further testing. At 10 years of follow-up, lung-cancer mortality was significantly lower in the screening group than in the control group (2.5 vs. 3.3 per 1000 person-years among male participants). Feb 06 Editorial Mortality Reduction with Low-Dose CT Screening for Lung Cancer...